HealthTech https://startupnationcentral.org/health-tech/ Your gateway to Israeli innovation Sun, 16 Jun 2024 08:47:30 +0000 en-US hourly 1 https://wordpress.org/?v=6.6.1 https://startupnationcentral.org/wp-content/uploads/2023/12/cropped-startupnationfavicon-2-32x32.png HealthTech https://startupnationcentral.org/health-tech/ 32 32 Israeli Femtech Products to Keep an Eye On https://startupnationcentral.org/blog/health-tech/israeli-femtech-products-to-keep-an-eye-on/ https://startupnationcentral.org/blog/health-tech/israeli-femtech-products-to-keep-an-eye-on/#respond Sun, 16 Jun 2024 08:44:40 +0000 https://startupnationcentral.org/?p=31957 With new products consistently added to a large base, Femtech is full of promise. This domain combines pioneering advancements in women’s health with cutting-edge technology to redefine the landscape of female-centric healthcare.  What Women’s Health Issues Do Femtech Products Address? Femtech encompasses four key pillars, each representing a critical facet of women’s health and well-being:  […]

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With new products consistently added to a large base, Femtech is full of promise. This domain combines pioneering advancements in women’s health with cutting-edge technology to redefine the landscape of female-centric healthcare. 

What Women’s Health Issues Do Femtech Products Address?

Femtech encompasses four key pillars, each representing a critical facet of women’s health and well-being: 

  • Fertility and Menstrual Health: An array of innovative solutions aids women in managing their reproductive cycles, offering tools for cycle tracking, ovulation prediction, and symptom management. 
  • Pregnancy and Maternal Health: Technologies designed to support expectant mothers through every stage of their journey, from prenatal care to postpartum recovery. 
  • Menopause and Perimenopause: Solutions providing relief and support to women navigating this transformative phase of life. 
  • Reproductive Health and Wellness: Resources and tools to empower women to take charge of their reproductive health journey. 
  • And more…

This sector is revolutionizing women’s health, laying the groundwork for a future where every woman can access personalized, comprehensive healthcare solutions tailored to her unique needs. 

Israel’s innovation ecosystem drives global advancements in women’s health with various companies and products. 

Femtech Devices 

Femtech devices that are reshaping the landscape of women’s health and wellness. Here are five leading devices developed by Israeli Femtech companies that are making a significant impact. 

1. Annabella Breast Pump

The Annabella Breast Pump is the first pump designed to simulate a baby’s tongue movement, aiming to stimulate milk production more naturally and efficiently. It features a soft silicone-covered breast shield and offers an adjustable size range to maximize comfort. By mimicking the wave-like motion of a baby’s tongue, the pump encourages the brain to produce more milk, offering a more pleasant pumping experience closer to natural breastfeeding.

Annabella Tech was founded in 2017 by Masha Waldberg. Masha, who struggled to breastfeed and pump, intimately understood her target market’s problem. With almost $8 million in funding, their product hit the market in Israel in February 2023 and has been capturing 5%—10 % of the market ever since. Now raising its seed round in funding, Annabella Tech looks to take its groundbreaking product to the US market and beyond.

Visit Annabella Tech’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

2. TrueLabor Maternal Fetal Monitor 

The TrueLabor™ Maternal Fetal Monitor from OB-Tools is a groundbreaking, noninvasive device revolutionizing labor and delivery monitoring. It provides maternal-fetal medicine specialists and OB-GYNs with the tools to accurately identify, measure, and evaluate uterine contractions and fetal heart rate. The system distinguishes between true and false labor signs, ensuring accurate, safe, and secure readings even in challenging conditions, thereby setting new standards in obstetric care. 

OB Tools, founded in 2003, is a mature company specializing in innovative maternal-fetal medicine and obstetrics solutions. The company focuses on developing noninvasive technologies to improve the accuracy and safety of labor and delivery monitoring, with its flagship product being the TrueLabor™ Maternal Fetal Monitor. As a well-established entity in the healthcare sector, OB Tools operates with a business model centered on providing advanced, reliable products to healthcare professionals, aiming to enhance obstetric care globally. 

Visit OB Tool’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

3. Fertissimo System for IVF Embryo Selection

The Fertissimo System, featuring the TCL Analyzer, is a state-of-the-art, non-invasive solution for optimal IVF embryo selection. By leveraging oxidative stress as a key biomarker of embryo viability, this system offers a novel approach to assessing embryos. The TCL Analyzer, a critical component of the Fertissimo System, enables the analysis of multiple embryos without disruption, completing each assessment swiftly in just eight minutes. This technology significantly enhances the IVF process, aiming to increase the chances of success.

Carmel Diagnostics, founded in 2009, is an innovative player in fertility diagnostics. The company has raised just under $7 million in its seed funding stage. Focused on enhancing IVF success rates through advanced technologies like the Fertissimo System, Carmel Diagnostics combines scientific research with practical application to support fertility journeys. Their approach to non-invasive embryo selection represents a significant advancement in reproductive technology.

Visit Carmel Diagnostic’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

4. The Hormone-Free IUB Ballerine

The IUB Ballerine is a hormone-free intrauterine device (IUD) designed by OCON Healthcare to provide a safe, next-generation contraceptive option that conforms to a woman’s anatomy. It represents a significant advancement in women’s health, offering a long-acting, reversible contraceptive method without the use of hormones, which can reduce the risk of side effects associated with hormonal contraceptives.

Founded in 2011, OCON Healthcare has been at the forefront of introducing innovative, hormone-free contraceptive solutions, raising $6.5 million in Series A funding to support its mission. Their product line, including the IUB Ballerine, IUB SEAD for managing abnormal uterine bleeding, and IUB PRIMA, showcases their commitment to providing safer, user-centered options in women’s healthcare. These products represent a significant leap forward in offering non-invasive, effective contraceptive and treatment options, emphasizing OCON’s dedication to advancing women’s health globally.

Visit OCON Therapeutics’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

5. The Illumigyn Gynescope® System

The Illumigyn Gynescope® System represents a breakthrough in gynecological care. It combines a cutting-edge optical device with advanced software for capturing and analyzing detailed gynecological images. This system facilitates a comprehensive examination process, enabling healthcare providers to obtain high-quality, magnified images for accurate diagnostics and treatment planning.

Illumigyn, founded in 2012 and currently in a Series A funding round with $38 million raised, is at the forefront of transforming gynecological healthcare. Their innovative Gynescope® System illustrates their dedication to enhancing diagnostic capabilities and improving outcomes in women’s health globally.

Visit Illumigyn’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

Femtech Apps & Software Products

Not to be left behind, Femtech apps and software also play a pivotal role, marking a new era of digital healthcare solutions tailored specifically for women. These platforms, leveraging the latest in AI, data analytics, and user-friendly interfaces, are revolutionizing how women manage their health, offering personalized insights and support across various stages of life.

Femtech apps and software are becoming essential for women in 2024, from breastfeeding tracking analysis to advancing IVF through AI. Below, we’ll highlight five innovations you should keep on your radar.

1. MyLee: Breastfeeding Tracking & Analysis Platform 

MyLee, by MyMilk Labs, is a groundbreaking device designed for breastfeeding mothers. It offers personalized insights into their breast milk’s nutritional content and production. This innovative tool enhances the breastfeeding experience by providing valuable feedback to improve breastfeeding practices. Available on the market, MyLee is a testament to MyMilk Labs’ commitment to supporting mothers in their breastfeeding journey.

Established in 2012, MyMilk Labs is in the midst of a pre-seed funding round, demonstrating its potential and commitment to revolutionizing maternal health. The company’s flagship product, MyLee, reflects its dedication to empowering breastfeeding mothers with actionable insights, facilitating a more informed and positive breastfeeding experience. With MyLee already making its mark on the market, MyMilk Labs is poised to contribute significantly to maternal and infant health.

Visit MyMilk Lab’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

2. INVU: Remote Fetal Non-Stress Testing Platform 

INVU by Nuvo offers a revolutionary approach to prenatal care with its remote fetal non-stress testing platform. This solution enables expectant mothers to monitor maternal and fetal heart rates from home. This solution represents a significant advancement in maternal healthcare, offering peace of mind and enhanced safety. It’s a testimony to the power of technology in transforming prenatal monitoring and care.

Nuvo was founded in 2007 and has made remarkable maternal and fetal health strides. Gaining FDA clearance in 2020 for its innovative monitoring technologies and partnering with Philips in 2022, Nuvo is at the forefront of prenatal healthcare innovation, providing solutions designed to improve outcomes for mothers and babies worldwide.

Visit Nuvo Group’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

3. EMA: AI Embryology Platform

EMA is an AI embryology platform created by AIVF. Using years of research combined with cutting-edge technology, AIVF leverages artificial intelligence to revolutionize the IVF process, giving embryologists advanced tools to analyze and select viable embryos. This platform represents a pivotal change in fertility treatments, aiming to increase success rates and support families on their journey to parenthood.

AIVF, established in 2018, is dedicated to enhancing fertility treatments through AI. With $25 million raised in Series A funding, AIVF is making significant contributions to reproductive medicine, demonstrating a strong commitment to improving the IVF experience for patients worldwide.

Visit AIVF’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

4. CHLOE: AI-Based IVF Decision Support  

CHLOE is at the forefront of integrating artificial intelligence into the in-vitro fertilization (IVF) journey, offering a decision-support platform that revolutionizes how fertility specialists approach treatment. By harnessing the power of AI to analyze vast amounts of data, CHLOE assists in making more informed decisions, potentially increasing the chances of successful pregnancies. This innovative tool is designed to bring clarity and precision to the IVF process, helping doctors and patients navigate the complex landscape of fertility treatments more confidently.

Fairtility, founded in 2019 and currently in a Series A funding round with $18.5 million raised, is pioneering in the field of fertility technology – including with the CHLOE product. Their focus on AI-driven solutions for IVF is setting new standards for success and efficiency in fertility treatments, offering hope and support to families worldwide.

Visit Fairtility’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

5. Expecting: AI-Based Surrogacy System 

Expecting is a product that tackles the many problems involved with surrogacy. It utilizes artificial intelligence to reimagine the surrogacy experience, offering a comprehensive system that streamlines surrogacy’s matching and management aspects. Its AI-driven approach simplifies the journey for intended parents and surrogates by optimizing compatibility and providing ongoing support. Expecting’s platform aims to make surrogacy more transparent, manageable, and accessible, reducing the stress and uncertainty that can often accompany such a significant life event.

Launched in 2020, Expecting uses AI to facilitate surrogacy processes. It is raising a seed round, with $1.5 million raised to date, as it continues innovating in the surrogacy sector. 

Visit Expecting’s Finder page for the most up-to-date information about this exciting Femtech company and its products.

The Future of Femtech Products

The femtech landscape in Israel is a vibrant blend of physical devices, apps, and software, each innovatively designed to cater to women’s health needs worldwide. This diverse array of solutions bridges gaps and addresses a wide spectrum of wellness areas.

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Israel’s Computational Biology Revolution: AI, Collaboration, and Shaping the Future https://startupnationcentral.org/blog/health-tech/israel-computational-biology-revolution/ https://startupnationcentral.org/blog/health-tech/israel-computational-biology-revolution/#respond Wed, 06 Mar 2024 09:43:36 +0000 https://startupnationcentral.org/?p=30942 Mati Gill, CEO, AION Labs The challenge of building an Israeli biotech ecosystem Israel has long been recognized as a hub for technological innovation, leading the way in industries ranging from cybersecurity and telecommunications to medical technology and artificial intelligence. However, the Startup Nation has traditionally faced challenges in replicating its high-tech success in the […]

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Mati Gill, CEO, AION Labs

The challenge of building an Israeli biotech ecosystem

Israel has long been recognized as a hub for technological innovation, leading the way in industries ranging from cybersecurity and telecommunications to medical technology and artificial intelligence. However, the Startup Nation has traditionally faced challenges in replicating its high-tech success in the biotechnology space. Advancements in computational biology are changing this.

Despite possessing all the necessary ingredients – including a robust and integrated healthcare system, world-leading academic institutions, and strong government support – Israel has yet to foster a globally competitive biotech ecosystem.

This is due to a range of factors, including a traditionally conservative industry dominated by multinational corporations – many of them considerably older than the modern state of Israel – and Israel’s relatively small market size.

In parallel, many aspects of Israel’s culture of entrepreneurship are not conducive to the biotech industry, which requires highly regulated processes, long-term thinking, and patience. The result is that, with a few exceptions, such as Teva Pharmaceuticals, we have generally not seen Israeli biotech startups become growth companies and multinational corporations building R&D centers in Israel, as has been the case in almost every other industry.

Israel’s AI proficiency spells promise for computational biology

Artificial intelligence is increasingly important to both the present and future of the biotech industry. The result is that greater emphasis is being placed on the ‘tech’ side of the biotech equation.

With the emergence of AI as the driving force in drug discovery and development, Israel has the opportunity to build a thriving and globally competitive ecosystem, alongside Boston, California, Germany, France, and the UK, among others.

This has already begun to take shape with multinationals increasing their investments in Israel. Organizations such as GSK and Verily recently opened research and development centers in Israel, while companies including Pfizer and AstraZeneca are making their first R&D investments in the country.

With advancements in AI and a growing recognition of the pivotal role machine learning will play in shaping biotech innovation, Israel is poised to become a strong ecosystem in computational biology.

Success through collaboration: co-development is critical for AI pharma innovation

Israel’s success in the biotech space, which is highly reliant on regulatory approvals and biological processes, hinges on collaboration. A co-development model, matching Israel’s AI and computational ingenuity with the vast experience of global pharmaceutical leaders, can expedite drug discovery and development, increase precision, and improve clinical trials.

Through leveraging AI and big data, these partnerships can identify new drug targets to treat more diseases and ultimately benefit more patients.

This model brings in experienced pharma executives from the outset to help define challenges and provide customer insights for a strong product-market fit. Additionally, the support of multinationals provides mentorship throughout the development process, validation of the technology, and access to proprietary data on which to build and refine AI models.

Such efforts show considerable promise, as exemplified by Insmed’s partnership with Google Cloud to accelerate drug discovery through a generative AI model. These collaborative models are already being replicated in Israel, as seen with Quris-AI’s collaboration with Merck KGaA to identify toxicity risks in the selection of drug candidates.

The potential of computational biology collaborations provides a blueprint for future endeavors in the Israeli biotech landscape.

The implications for computational biology in Israel

Israel’s emergence as a hub of innovation in computational biology carries profound implications for both the domestic and global biotech landscape. The nation’s academic leaders are becoming increasingly entrepreneurial and pursuing careers beyond academia, applying their ideas to create tangible products that can provide practical good in the world.

This has already garnered interest from multinational corporations, positioning the nation as a focal point for cutting-edge research and development. We are now witnessing the emergence of a new generation of startups that make Israel a relevant computational biology hub, attracting investment from global VCs and pharmaceutical developers.

The combination of high-quality academic research and contributions from multinational entities highlights Israel’s potential to shape the future of computational biology.

On the cusp of a new era in computational biology

Israel is poised to shape the future of computational biology, contributing to advancements that transcend geographical boundaries and traditional barriers. As the country’s nascent biotech ecosystem continues to cultivate international partnerships and harness the power of AI, it is becoming highly relevant for global investment and scientific breakthroughs in computational biology. With a commitment to addressing industry needs and shaping the future of biotech, Israel’s computational biology revolution is quickly moving from the realm of possibility to a promising reality.


Mati Gill is CEO of AION Labs, a venture studio with a first-of-its-kind company creation model for new start-ups utilizing AI for drug discovery and development. Supported by the Israeli Government, AION Labs was formed from the unique alliance of Pfizer, Amazon Web Services, AstraZeneca, Teva Pharmaceuticals, Merck, the Israel Biotech Fund, Amiti Ventures, and BioMed X. Before founding AION Labs, Mati was a senior executive at Teva Pharmaceuticals and served as Chief of Staff for Israel’s Minister of Public Security. He is an IDF veteran (Maj. res.) and founder of the Sanhedrin Forum for young Israeli professionals. A qualified attorney, Mati holds an LLM and an MBA in Healthcare and Innovation, both from Reichman University. He currently serves on the boards of the Israel Advanced Technology Industries Association (IATI) and the Israel America Chamber of Commerce (AmCham).

aion labs computational biology israel
Photo credit: Elad Malka

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AI in Medical Imaging: An Overview  https://startupnationcentral.org/blog/health-tech/ai-in-medical-imaging-an-overview/ https://startupnationcentral.org/blog/health-tech/ai-in-medical-imaging-an-overview/#respond Tue, 05 Mar 2024 11:42:47 +0000 https://startupnationcentral.org/?p=30927 The fusion of Artificial Intelligence (AI) with medical imaging is revolutionary in healthcare diagnostics. AI, with its capability to analyze and interpret complex data, is transforming the landscape, offering unprecedented accuracy and efficiency in disease detection, diagnosis, and treatment planning.  According to a survey conducted by Startup Nation Central at the end of November 2023, […]

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The fusion of Artificial Intelligence (AI) with medical imaging is revolutionary in healthcare diagnostics. AI, with its capability to analyze and interpret complex data, is transforming the landscape, offering unprecedented accuracy and efficiency in disease detection, diagnosis, and treatment planning. 

According to a survey conducted by Startup Nation Central at the end of November 2023, involving 123 leaders active in the Israeli tech ecosystem, Artificial Intelligence (AI) has emerged as a sector of high potential and will have a significant role in driving innovation and growth in the 2024 Israeli tech landscape – in particular with medical imaging.

AI in Israeli tech 2024

Understanding AI and its Role in Medical Imaging 

By integrating AI technologies like machine learning and deep learning, medical imaging has seen substantial improvements in accuracy, efficiency, and predictive analytics. AI’s ability to process and analyze vast datasets enhances disease detection, diagnosis, and treatment planning. This integration not only accelerates diagnostic processes but also reduces human error, ensuring quicker and more reliable patient care.

What is artificial intelligence? 

At its core, AI encompasses a wide range of technologies capable of performing tasks that typically require human intelligence. Among these, machine learning and deep learning stand out for their ability to learn and improve from experience without being explicitly programmed, making them particularly suited for analyzing the vast amounts of data generated in medical imaging. 

What is medical imaging? 

Medical imaging is a crucial technique in modern healthcare, allowing clinicians to visualize the interior of the body for analysis and medical intervention. It plays a vital role in the early detection of diseases, monitoring of conditions, and guiding treatment decisions, encompassing technologies such as X-rays, CT scans, MRI, and ultrasound. 

How is AI used in medical imaging? 

AI enhances medical imaging in: 

  1. Detection and Diagnosis: AI algorithms excel at identifying subtle patterns in imaging data, aiding in the early detection of diseases like cancer. 
  1. Predictive Analytics: By analyzing imaging data alongside patient history, AI can predict disease progression and outcomes. 
  1. Image Segmentation: AI automates the segmentation of images, isolating specific areas for detailed analysis. 

Key Benefits of AI in Medical Imaging 

The advent of AI in medical imaging brings a transformative shift in healthcare, offering multifaceted benefits that extend far beyond the confines of traditional diagnostic methods. The precision and efficiency introduced by AI not only enhance diagnostic accuracy but also streamline healthcare workflows. 

Improved accuracy 

AI’s role in medical imaging marks a significant leap in diagnostic accuracy. Algorithms trained on extensive datasets can precisely pinpoint disease markers and anomalies. This improvement in accuracy is pivotal for early detection, where AI’s ability to discern subtle indicators can lead to early intervention, significantly improving patient outcomes. 

Enhanced predictive analysis 

Extending beyond mere detection, AI offers predictive insights that were previously unattainable. By analyzing imaging data in conjunction with patient histories, AI models can forecast disease progression and potential health outcomes. This predictive capability is invaluable for personalized medicine, allowing healthcare providers to tailor treatment plans to individual patient profiles, improving the efficacy of interventions. 

Greater efficiency and speed 

AI dramatically accelerates the medical imaging process, enabling rapid analysis and interpretation of images. This acceleration is crucial, reducing diagnostic wait times and allowing for quicker treatment initiation. In emergency medical scenarios, where time is of the essence, AI’s ability to swiftly process and analyze images can be life-saving. 

Reduction of human error 

Automating the analysis of medical images with AI minimizes the risk of oversight and human error. By handling high-volume, routine tasks, AI allows medical professionals to concentrate on more complex diagnostic challenges, enhancing the overall quality of care and ensuring a higher level of diagnostic reliability. 

While AI in medical imaging presents these significant benefits, addressing the accompanying challenges is essential for maximizing its potential and ensuring its ethical and secure application in healthcare. 

Challenges Facing AI in Medical Imaging 

Despite its considerable advantages, the integration of AI into medical imaging is not without its challenges. These hurdles span technical, ethical, and operational domains, necessitating concerted efforts to address them effectively. 

Data privacy and security considerations 

As AI systems process vast amounts of sensitive patient data, ensuring the privacy and security of this information is paramount. The risk of data breaches poses a significant concern, underscoring the need for robust cybersecurity measures and stringent compliance with data protection regulations. 

Ethical aspects of AI 

The deployment of AI in healthcare raises complex ethical questions, particularly concerning accountability in AI-driven diagnosis and treatment decisions. Establishing clear guidelines and ethical standards is essential to navigate these issues, ensuring AI is used responsibly and in the best interest of patients. 

Limited understandability and transparency

The inherent complexity of AI algorithms — often called the “black box” problem — can hinder their acceptability among healthcare professionals. Efforts to increase the transparency and explainability of AI systems are crucial in building trust and facilitating their broader adoption. 

By addressing these challenges, the potential of AI in medical imaging can be fully realized, paving the way for a future where healthcare is more accurate, efficient, and personalized than ever before. 

Israel Leading AI Innovation 

In the rapidly evolving field of medical imaging, AI-driven innovations are not just enhancing diagnostic accuracy but fundamentally reshaping the approach to patient care. Real-world applications of AI in medical imaging, such as AI-driven radiology and AI in cancer detection, showcase its potential to significantly improve diagnostic accuracy and patient outcomes – and Israel’s determined and bold innovators are leading the way. 

Aidoc: Enhancing real-time image analysis 

Aidoc stands at the forefront of Israeli innovation in AI for medical imaging. It provides advanced AI solutions that analyze medical images in real-time, integrating smoothly into doctors’ existing workflows. This technology supports medical professionals by augmenting their capabilities, ensuring no disruption to their daily routines while enhancing diagnostic speed and accuracy. 

Zebra Medical Vision: Early disease detection through deep learning 

Zebra Medical Vision has carved a niche in early disease detection by employing deep learning to scrutinize medical scans. This Israeli company’s technology spots early signs of various conditions, including liver and breast cancers, osteoporosis, and cardiovascular disease. Zebra was acquired by Nanox in 2021.

Israel’s vibrant ecosystem 

A host of companies from Israel’s vibrant tech ecosystem are developing groundbreaking solutions applying artificial intelligence solutions to medical imaging. View a full list of companies on Finder: 

Impact of AI on Medical Professionals 

 
The advent of AI is reshaping the roles of professionals in medical imaging. While there are concerns about AI replacing radiologists, the current trend suggests AI will augment professionals’ capabilities rather than replace them, necessitating new skills and training. 

Future of AI in Medical Imaging 

AI in medical imaging represents a significant leap forward in healthcare technology. With its ability to improve diagnostic accuracy, predict outcomes, and streamline processes, AI is set to play a crucial role in the future of healthcare. While challenges remain, the potential benefits are too significant to ignore. As the technology evolves, it will undoubtedly continue to transform the field, promising better patient outcomes and more efficient healthcare delivery. 

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Roche for a Better Future: Ophthalmology Innovation Challenge Pilot & Program Finalists  https://startupnationcentral.org/blog/health-tech/roche-ophthalmology-innovation-2023/ https://startupnationcentral.org/blog/health-tech/roche-ophthalmology-innovation-2023/#respond Sun, 25 Feb 2024 10:07:57 +0000 https://startupnationcentral.org/?p=30825 Ophthalmology innovation is increasingly relevant as a rapidly aging global population means more vision-impaired patients per capita. Retinal diseases are a major cause of vision impairment and blindness worldwide, affecting millions of people. These conditions range from age-related macular degeneration (AMD) and diabetic retinopathy to retinal detachment and inherited retinal diseases. Roche, Startup Nation Central, […]

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Ophthalmology innovation is increasingly relevant as a rapidly aging global population means more vision-impaired patients per capita.

Retinal diseases are a major cause of vision impairment and blindness worldwide, affecting millions of people. These conditions range from age-related macular degeneration (AMD) and diabetic retinopathy to retinal detachment and inherited retinal diseases.

Roche, Startup Nation Central, and Beilinson Hospital share a common vision of providing enhanced digital health solutions that significantly improve retina patients’ lives and support their caregivers by enabling monitoring, enhancing patient support, and optimizing screening and diagnosis.   

Main Challenges 

  • Prevalence: The global prevalence of retinal diseases is increasing, partly due to aging populations and the rising incidence of diabetes. The projected number of people living with the two of the leading causes of vision loss – Neovascular Age-related Macular Degeneration (nAMD) and Diabetic Macular Edema (DME) – is set to grow from 20 and 21 million people respectively in 2020 to approximately 29 and 43 million in 2024.  
  • Diagnosis and Access: Early diagnosis and access to treatment are significant challenges, especially in low-resource settings. Many retinal diseases progress silently until they reach advanced stages, making early detection critical.  
  • Treatment: While there have been advances in treatments, such as anti-VEGF therapy for AMD and laser therapy for diabetic retinopathy, these treatments require prompt administration and ongoing monitoring. 

Leading Ophthalmology Innovation Solutions 

Innovative technologies are transforming the landscape of retinal disease management: 

  • AI-based Diagnostic Tools: AI algorithms are being developed to analyze retinal images with high accuracy, enabling early detection of diseases like diabetic retinopathy and AMD. 
  • Remote Monitoring Services: Platforms like Notal Vision offer remote monitoring for patients with retinal diseases, facilitating early intervention and personalized care. 
  • Wearable and Portable Devices: Advances in wearable and portable imaging devices are making retinal screenings more accessible, allowing for early detection and monitoring outside traditional clinical settings. 

Israel’s Global Role in Ophthalmology Innovation

Israel is at the forefront of developing digital health solutions for retinal diseases – as shown by the collaboration between Roche, Startup Nation Central, and Beilinson Hospital.  

This partnership is an extension of Israel’s commitment to innovation in healthcare, including in ophthalmology. Israeli startups and research institutions are making significant contributions to the field with cutting-edge technologies and platforms aimed at improving diagnosis, treatment, and patient engagement.  

The Roche for a Better Future Ophthalmology Innovation Challenge & Pilot Program highlights Israel’s role in driving global innovation in retinal health, offering a platform for startups to showcase their solutions.

Out of the dozens of applicants, only six finalists were chosen to compete in the global showcase final event. 

Roche for a Better Future Finalists

The Roche for a Better Future Ophthalmology Innovation Challenge & Pilot Program is a groundbreaking platform that offers a unique package for the winning startup.  

This includes a clinical pilot at Beilinson Hospital, valued at up to 200,000 NIS, comprehensive mentorship, exposure to IIA acceleration programs, a fast track for submission to Helsinki Committees, global exposure, and the chance to collaborate with Roche. 

Here are the innovative companies that have made it to the final round of the Ophthalmology Innovation Challenge:

WINNER ANNOUNCED MARCH 4th 2024: NOTAL VISION

Notal Vision provides remote patient monitoring services for retinal diseases, extending eye disease management from the clinic to the home to improve vision outcomes. Their Notal Home OCT is a first-of-its-kind AI-enabled program for monitoring neovascular Age-related Macular Degeneration (nAMD) using home-based OCT technology.

FINALISTS

AEYE Health offers fully autonomous, AI-based diagnostic screening solutions for retinal imaging, focusing on delivering best-in-class results. They have developed an innovative AI-based diagnostic screening system for diabetic retinopathy, which has received FDA clearance. AEYE Health has also announced partnerships to enhance point-of-care diabetic retinopathy screening with their AI technology. Their system provides analysis and diagnostic results within 60 seconds, aiming to revolutionize diabetic retinopathy screening.

GistMD offers a personalized patient engagement platform that provides a flexible and patient-centered framework for bridging communication gaps between patients and healthcare providers. Their platform is being implemented in over 34 medical centers globally, aiming to empower patients in their healthcare journey with personalized educational content.

The Computer-Aided Surgery and Medical Image Processing (CASMIP) Lab, led by Prof. Leo Joskowicz, conducts groundbreaking research in AI for eye disease diagnosis using various imaging techniques. The lab focuses on developing disease progression monitoring technologies and has significantly contributed to medical image processing and computer-aided surgery.

Xoltar is an AI-powered patient engagement and adherence platform that offers a conversational AI platform designed for long-lasting patient engagement, focusing on medical adherence. Their mobile app enables interaction with generative AI-based accountability partners in real-time, aiming to improve patient adherence and engagement through personalized interactions.

Looking Towards a Better, Brighter Future

The fight against retinal diseases is being bolstered by technological advancements and international collaborations.

Israel’s vibrant tech ecosystem, characterized by innovative startups and research excellence, plays a pivotal role in shaping the future of retinal disease management.  

Through initiatives like the Roche Ophthalmology Innovation Challenge, Israel continues to contribute to global efforts in improving the lives of patients with retinal diseases, demonstrating the country’s leadership in healthcare innovation. 

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Empowering Women’s Health: The Rise of Israeli Femtech in 2024  https://startupnationcentral.org/blog/health-tech/israeli-femtech-2024/ https://startupnationcentral.org/blog/health-tech/israeli-femtech-2024/#respond Mon, 12 Feb 2024 10:05:42 +0000 https://startupnationcentral.org/?p=30710 Femtech, a term coined to describe technologies focused on women’s health, has emerged as a dynamic and rapidly evolving sector. It encompasses a range of solutions from healthcare to wellness, tailored specifically for women.  The global surge in femtech is notable, with Israel playing a significant role. The country’s advancements in this field position it […]

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Femtech, a term coined to describe technologies focused on women’s health, has emerged as a dynamic and rapidly evolving sector. It encompasses a range of solutions from healthcare to wellness, tailored specifically for women. 

The global surge in femtech is notable, with Israel playing a significant role. The country’s advancements in this field position it as a leader in innovation and development. 

More than Health Tech 

Femtech is not limited to healthcare; it spans various technologies. This includes reproductive health, menstrual cycle tracking, and fertility solutions, and extends to wellness, mental health, and lifestyle products designed for women. The scope extends into finance and safety, offering holistic solutions that address the unique needs of women in various aspects of life. 

The Global Femtech Landscape in 2024 

The global femtech sector has grown significantly, with approximately 1,800 companies and a cumulative investment of $1.6 billion as of April 2023. This growth reflects increased awareness and investment in the sector, highlighting its rising importance in the technology and health industries. 

Israel stands out in the global femtech market, boasting the fourth largest number of companies and ranking second in global investment in the sector with over 100 companies dedicated to women’s health and wellness. The last five years have seen a surge in Israeli femtech companies and investment, indicating a robust and growing ecosystem. 

Israeli Femtech: Key Verticals and Innovations 

Israeli femtech is diverse, with five main verticals: pregnancy, fertility, health, wellness, and oncology. Notably, pregnancy and fertility solutions represent around 43% of these companies. Israeli femtech innovations include advanced fertility tracking apps and digital platforms for comprehensive women’s health monitoring. 

Here are some notable examples of Israeli femtech companies: 

  • MobileODT:  Specializing in cervical cancer screening, MobileODT uses advanced imaging and AI technology to enhance early detection. Their EVA System offers a smart, mobile colposcope designed to be used by healthcare professionals for cervical cancer screening, improving accessibility and accuracy. 
  • ThermoMind: Leveraging next-generation thermal imaging modality based on AI-enhanced dynamic thermography, ThermoMind is on a mission to save lives through early breast cancer screening and detection.   
  • Shela: A Sheba Medical Center and Bar-Ilan University joint venture, developing Maternal-Fetal Precision Medicine predictions based on clinical data integrated with multiomics. 
  • AIVF: AI-powered IVF solutions for clinics, labs, and patients to help increase the certainty of a successful journey to parenthood. 
  • Livia: A unique solution for menstrual pain relief using electrical micro-pulses to alleviate menstrual cramps, providing a drug-free alternative for pain management during menstruation. 
  • OCON Healthcare: Specializing in women’s intrauterine health, OCON Healthcare has developed the IUB, a hormone-free intrauterine ball used as a long-term reversible contraceptive. This product is designed to be safer and more comfortable than traditional intrauterine devices (IUDs). 
  • Identifai Genetics: Cutting-edge bioinformatics technology that offers an early and comprehensive prenatal screening test for genetic syndromes. Using a simple blood test from the mother during the first trimester of the pregnancy, our proprietary data science algorithms provide a high-resolution yet comprehensive perspective of the fetus’s health at an early stage of the pregnancy. 

These companies represent the diversity and innovation within the Israeli femtech sector, addressing various aspects of women’s health from cancer screening to maternal health, breastfeeding, menstrual pain, and beyond. Their solutions are not only innovative but also contribute significantly to improving the quality of life and health outcomes for women globally. 

Challenges and Opportunities  

The sector faces challenges such as investor bias and the misconception of women’s health as a niche market, despite women making up half the global population. Opportunities lie in underexplored areas like menopause and endometriosis. There’s a need for more diverse funding to support a wider range of femtech innovations. 

Trends and Predictions 

Femtech is expected to continue its upward trajectory, with a focus on personalized and AI-driven healthcare solutions. The future of the sector is also shaped by the increasing presence of women in leadership and investment roles, influencing its direction and growth. 

Spotlight on Israeli Femtech Leading the Way Forward 

Israel’s position in the femtech ecosystem drives global advancements in women’s health technology, highlighting its potential as a leader in this field. Israel’s strong healthcare system and extensive digital health records position it as a potential leader in the field. There’s a noticeable trend of increasing Israeli investment in femtech, moving from reliance on foreign investors to domestic funding and support and indicating a strong belief in the sector’s potential. 

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Nutrition Tech: The Future of Health and Wellness https://startupnationcentral.org/blog/health-tech/nutrition-tech/ https://startupnationcentral.org/blog/health-tech/nutrition-tech/#respond Sun, 21 Jan 2024 13:52:56 +0000 https://startupnationcentral.org/?p=30477 By Eyal Shimoni As a senior research fellow at the Samuel Neaman Institute and a scientific and tech advisor, Eyal Shimoni brings a wealth of knowledge and a unique perspective to the Nutrition Tech landscape. A board member and head of the Nutrition Tech initiative at Health Tech Valley, Eyal is pioneering the integration of […]

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By Eyal Shimoni

As a senior research fellow at the Samuel Neaman Institute and a scientific and tech advisor, Eyal Shimoni brings a wealth of knowledge and a unique perspective to the Nutrition Tech landscape. A board member and head of the Nutrition Tech initiative at Health Tech Valley, Eyal is pioneering the integration of data-driven solutions into nutritional science and healthcare. Eyal is also a writer and ultra-marathon runner.

eyal shimoni

Nutrition Tech is emerging at the intersection of healthcare, technology, and nutrition, aiming to revolutionize how we understand and manage our health through diet and lifestyle. This sector is harnessing the power of technology, data analytics, and personalized approaches to foster a healthier society, making Nutrition Tech a pivotal element in the future of health and wellness.

There is a clear continuum between diet, physical activity, and health, whether it is for maintaining good health, treating a specific illness, or recovering from a disease or medical procedure. This continuum is where we have the opportunity to nurture solutions based on data sharing, the convergence of technologies, and tailoring solutions for populations and individuals (personalized medicine and nutrition).

Overall, Nutrition Tech and Health Tech are connected through their shared goal of promoting well-being, longevity, and healthy lifestyle habits. The Health Tech Valley is where we merge these elements in the Nutrition Tech lab initiative.

Economic Motives and Industry Challenges

In the interests of preventative medicine, a person’s health should be managed with a broad and holistic view that sees his entire lifestyle first, with treatment for disease only at the end. This also has a clear economic motive: the costs of drug development and the heavy burden of regulation for pharmaceutical companies in developing new clinical solutions means that companies are looking for new channels and innovative products that contribute to solving health challenges beyond the realm of classical pharmaceuticals.

On the other side of the coin, agriculture and food companies are likewise facing several challenges: the increase in diseases related to poor lifestyle and poor nutrition (obesity, diabetes, blood pressure, heart disease, etc.) is creating a crisis of confidence among consumers and regulators. In addition, rising prices for energy, raw materials, and labor costs are eroding revenue margins. Beyond the challenges facing pharmaceutical and food industries, climate change is disrupting global supply chains – which also creates significant pressure for companies to look at developing products with added value beyond their basic nutritional value.

The Trend of Personalization and Data Utilization

Personalization is a significant trend in Health Tech. Consumers are asking for products that suit them personally and will help them maintain a healthy lifestyle with an emphasis on nutrition. This continuum between food and medicine creates an ocean of opportunities – to feed, prevent, manage a clinical condition, treat a medical condition, or even provide a cure.

Along with this, we are experiencing rapid and extremely significant leaps in the ability to collect data using a variety of tools and platforms. The use of data and technology to monitor, analyze, and optimize health and nutrition outcomes, involves collecting and analyzing several types of data, such as personal health information, biometric measurements, dietary information, and lifestyle factors, to make informed decisions and recommendations for individuals or populations. Robust collection of data can drive insights related to Personalized Health Tracking; Nutritional Analysis; Behavior Change and Coaching; Remote Monitoring and Telemedicine; and Population Health Management.

Building the Nutrition Tech Lab

Nowadays, there are numerous ways that data can be collected about our physical activity (mobile, wearables, and more), our health (medical files at our doctor, in the clinics and hospitals we visit), genetic information from various databases – national or private, the purchase of our food from retailers and others, our actual food consumption (digital diaries, Instagram photos, etc.), our lifestyle (sleep, movement, etc.), continuous physiological indicators (sugar monitors, heart rate monitors, blood pressure monitors, etc.), and many more.

But data collection, as significant as it is, is only the beginning. Data analytics capabilities – human, mechanical, and artificial (AI) – are improving at a rate that disrupts Moore’s Law. To utilize this data, we are building the “Nutrition Tech lab” where multiple stakeholders can address challenges using collaborative approaches to data. This approach optimizes the potential of Nutrition Tech communities, in which multiple partners share access to data-driven insights, for the development of innovative solutions.

Data-Driven Strategies for Health and Nutrition Tech

Preventing, treating, and curing clinical states through nutrition involves specific evidence-based dietary approaches. Solutions and strategies leveraging health data are being developed for Cardiovascular Health; Diabetes Management; Gastrointestinal Disorders; Kidney Disease; Cancer Treatment Support; and Malnutrition and Nutritional Deficiencies. Data and nutrition should work together to enhance preventive strategies and can utilize data to explore the relationships between diet, health outcomes, and disease prevention: strategies, interventions, and technologies aimed at improving nutrition and reducing the risk of food-related diseases.

With the support of Cloud and OpenAI computing capabilities, this can be done on a mass scale, in groups, clusters, or single humans. Some fields affected by the insights and solutions are Personalized Nutrition; Behavioral Change and Education; Personal Nutrition; Health Tracking and Apps; Guidelines and Policies; and Regulations.

AI Computing Capabilities and the Future of Nutrition Tech

Cloud and OpenAI computing capabilities also empower us to provide an infrastructure that will grant access to insights derived from numerous partners of the community – without breaching their confidentiality. Data sharing is a powerful tool for new insights, for the development of novel solutions, and for reducing development costs and shortening time to market.

A Nutrition Tech ecosystem connects global partners: companies, data providers, entrepreneurs, and researchers who work together to enable data-driven innovative solutions and opportunities such as bioactive molecules, products, formulation, devices, digital tools, raw materials, and many more.

By intertwining technology, data analytics, and personalized nutrition, this initiative is not just addressing current health challenges but is also paving the way for a future where preventive healthcare and personalized treatment strategies are the norm. The commitment to innovation and the holistic approach to health management are instrumental in driving a transformative journey in healthcare. As we move forward, the potential of Nutrition Tech to reshape our understanding of health, diet, and lifestyle is immense, promising a future where well-being is data-driven, personalized, and accessible to all.


HealthTech Valley brings together academia, medical centers, and industry partners to reimagine healthcare and create a better future for all. HealthTech Valley accelerates health-enhancing technologies, while collaborating with global leaders, to strengthen global & local communities’ wellbeing.

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Tech Transfer and Scaling Health and Climate Innovation Solutions   https://startupnationcentral.org/blog/climatetech/tech-transfer-health-and-climate-innovation/ https://startupnationcentral.org/blog/climatetech/tech-transfer-health-and-climate-innovation/#respond Mon, 25 Dec 2023 10:03:18 +0000 https://startupnationcentral.org/?p=30070 In a world increasingly confronted with climate change effects and healthcare challenges, the transfer and scaling of innovative technologies are crucial for driving sustainability goals. Israel’s success in tech transfer offers a valuable blueprint for the global adoption of climate and health technologies, providing practical insights into how innovative solutions can be implemented across geographical […]

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In a world increasingly confronted with climate change effects and healthcare challenges, the transfer and scaling of innovative technologies are crucial for driving sustainability goals. Israel’s success in tech transfer offers a valuable blueprint for the global adoption of climate and health technologies, providing practical insights into how innovative solutions can be implemented across geographical and socio-economic contexts. 

The Role of Tech Transfer

Technology transfer involves sharing innovative solutions developed in academic and research environments. It’s about adapting and scaling these solutions to effectively meet local needs. Scaling innovation is essential for amplifying the impact of these solutions and ensuring they address vast and varied needs. 

Technology transfer is critical in the global response to environmental and climate challenges. It facilitates innovative solutions that can reduce greenhouse gas emissions, enhance energy efficiency, and support sustainable development.  

Transferring medical technologies, pharmaceutical innovations, and healthcare management systems is crucial in the healthcare sector for improving patient outcomes, enhancing the quality of care, and making healthcare more accessible and affordable.

Leveraging Israel’s Experience in Tech Transfer 

Israel, known as the “Startup Nation,” is a leader in technology transfer from academic and research institutions to industrial applications worldwide. This success is backed by real-world examples of Israeli innovations that have been successfully transferred and scaled worldwide. The country’s research institutions, startups, and industry partnerships contribute to a robust ecosystem supporting effective tech transfer. 

One of Israel’s strengths is adapting climate technology solutions from the lab to diverse contexts, ensuring they are not only technologically advanced but also culturally and environmentally appropriate. The country’s contribution to global health tech through technology transfer is multifaceted, involving innovative technologies, international collaborations, and a dynamic ecosystem that supports continuous innovation.

Why Investors Should Pay Attention to Israel

  • Innovative Edge: Israeli tech transfers are at the forefront of climate and health technology, offering cutting-edge solutions with the potential for high returns.
  • Global Scalability: The adaptability of these technologies to various global contexts ensures a wide market reach and scalability.
  • Attractive Valuations: Current macroeconomic shifts and local conditions have led to attractive valuations in the tech sector, presenting a prime investment opportunity.
  • Sustainability and Impact: Investing in climate technology aligns with growing sustainability and social responsibility trends, appealing to a broader base of impact-focused investors.

Examples of Successful Israeli Tech Transfer 

ImaginDairy creates animal-free dairy products using precision fermentation technology, producing milk proteins through microflora. 

  • Background: Based on 15 years of research spearheaded by Prof. Tuller from Tel Aviv University, ImaginDairy creates non-animal versions of whey and casein proteins essential for replicating various dairy products. Operating from Yokne’am, the research team consists of 30 multidisciplinary experts specializing in microbiology, computational systems, and biotechnology. The Kitchen FoodTech hub, based in Israel, backs the company. 
  • Global Impact: With the growing demand for plant-based and alternative dairy products, ImaginDairy’s technology could revolutionize the dairy industry and address environmental and ethical concerns. The startup has successfully secured $28 million in seed funding from various investors, including Target Global, Strauss Group, Emerald Technology Ventures, Green Circle Foodtech Ventures, Collaborative Fund, and New Climate Ventures. 

Alpha Tau Medical developed Alpha DaRT, an innovative radiation therapy for treating solid tumors. 

  • Background: Alpha Tau Medical, founded in 2016 by CEO Uzi Sofer, is dedicated to developing and commercializing Alpha DaRT™ (Diffusing Alpha-emitters Radiation Therapy), an invention by Professors Itzhak Kelson and Yona Keisari from Tel Aviv University. The company aims to bring this innovative alpha radiation technology to cancer patients globally. Alpha Tau is currently conducting several clinical and pre-clinical studies in partnership with various medical and educational institutions worldwide. 
  • Global Impact: Alpha DaRT is undergoing clinical trials worldwide. It offers a new treatment option for various cancers and could significantly improve cancer treatment outcomes. 

Aleph Farms is an Israeli cellular agriculture company founded in 2017 specializing in food technology.

  • Background: Aleph Farms produces meat directly from animal cells, offering a sustainable and ethical alternative to traditional meat production. Co-founded in 2017 by Prof. Shulamit Levenberg and Didier Toubia, Aleph Farms is based in Rehovot, Israel. The company’s foundation is deeply rooted in university research, particularly from the Technion – Israel Institute of Technology, on tissue engineering and regenerative medicine, and developed in partnership with “The Kitchen,” a food tech incubator from the Strauss Group Ltd. 
  • Global Impact: Addressing global concerns about food security, animal welfare, and environmental impact, Aleph Farms is scaling up production and collaborating with regulatory agencies worldwide to bring its products to the international market. 

Copaxone (Teva Pharmaceutical Industries) is the leading medication for managing multiple sclerosis, benefiting patients worldwide.

  • Background: Copaxone is a medication for treating multiple sclerosis, marking a significant development in neurology and autoimmune diseases. Copaxone (copolymer-1) has a remarkable development history spanning nearly three decades, culminating in its FDA approval in December 1996. This journey from laboratory synthesis to an FDA-approved drug for MS reflects scientists’ and clinicians’ persistence, perseverance, and collaborative efforts over several decades. 
  • Global Impact: As one of the most widely prescribed treatments for multiple sclerosis globally, Copaxone has not only benefited patients worldwide but also positioned Israel as a leader in pharmaceutical innovation. 

Strategies for Global Adoption of Climate Solutions 

Adopting technologies on a global scale involves more than just the transfer of hardware or software. It requires a holistic approach incorporating strategic elements to ensure these solutions’ successful and sustainable implementation:

  • Capacity Building and Knowledge Transfer 

Successful implementation of scaled solutions requires capacity building and knowledge transfer. Communities and countries need the skills and knowledge to use, maintain, and develop these technologies, ensuring sustainability and adaptability to local conditions. 

  • Public-Private Collaborations 

Collaborations between governments, private sector entities, and research institutions are crucial in accelerating tech transfer. These partnerships provide funding, expertise, and infrastructure to support the adoption and scaling of solutions, navigating regulatory landscapes, and gaining public acceptance. 

  • International Collaborations and Networks 

International collaborations and networks are pivotal in sharing best practices and facilitating the transfer of climate and health solutions. They bridge the gap between countries with advanced technologies and those in need, providing a platform for exchanging ideas, fostering innovation, and building long-term cooperation. 

  • Long-term Viability and Sustainability 

Ensuring transferred climate solutions’ long-term viability and sustainability involves technological robustness, economic feasibility, and social acceptability. Solutions must be cost-effective and environmentally friendly to ensure widespread adoption and maintenance. 

Israel as a Model for Tech Transfer Success 

Technology transfer and scaling are vital in confronting global climate challenges. By drawing insights from Israel’s tech transfer experiences, we can foster global collaboration and accelerate the adoption of innovative climate solutions. These solutions must be adaptable to diverse contexts, supported by robust capacity building, and sustained through public-private and international collaborations. As we address climate change, the global community must unite to share, adapt, and scale innovative solutions, ensuring a sustainable future for all. 

At Startup Nation Central, our team of experts forges strategic partnerships. It advances collaboration between global entities and Israel’s tech ecosystem of impatient innovators, creating ideal conditions for high-potential investment. This way, real climate and health solutions can be tested, adopted, and scaled. Climate change targets can be met to ensure future generations inherit a truly sustainable and livable world.​

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Digital Innovation in Mental Health Tech: Israel’s Approach https://startupnationcentral.org/blog/health-tech/innovation-in-mental-health-tech-israels-approach/ https://startupnationcentral.org/blog/health-tech/innovation-in-mental-health-tech-israels-approach/#respond Sun, 03 Dec 2023 13:02:56 +0000 https://startupnationcentral.org/?p=28975 In the wake of October 7th and the trauma it inflicted, several companies in Israel’s health tech sector have been pivotal in addressing emerging mental health needs. Over 80 Israeli health tech companies are revolutionizing mental health support, particularly in the context of PTSD and the challenges arising from the experience of armed conflict. The […]

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In the wake of October 7th and the trauma it inflicted, several companies in Israel’s health tech sector have been pivotal in addressing emerging mental health needs. Over 80 Israeli health tech companies are revolutionizing mental health support, particularly in the context of PTSD and the challenges arising from the experience of armed conflict.

The Rising Need for Mental Health Tech Solutions

The events of October 7th have shone a light on the critical need for accessible mental health support. Dr. Iris Adler, Health Tech Sector Lead at Startup Nation Central, emphasizes the urgency of this need:

“Israeli tech is characterized by its ability to respond to existing needs quickly – and now the need is significant. It is expected that the number of companies in the field will increase and the existing ones will continue to develop.”

“The real challenge is in finding relevant solutions that support mental health, rehabilitation, and comprehensive treatment, alongside maintaining professional methodologies and accuracy. It’s important to note the significant effort in hospitals and health funds that have quickly integrated new technologies.”

These companies are not just filling a gap in mental health services; they are redefining the approach to mental health care. The focus is not only on developing solutions but also on ensuring these solutions are relevant, effective, and can be seamlessly integrated into the existing healthcare infrastructure.

The Broader Mental Health Tech Landscape in Israel

The mental health startup ecosystem in Israel has unique characteristics. The first wave of Israeli startups in mental health emerged before the pandemic, with new startup formations remaining active, especially compared to other sectors.

These startups focus on self-care and treatment, often without considering the infrastructural needs of healthcare systems. This gap between innovation and implementation has led to a proliferation of wellness-oriented startups.

Key Trends and Insights

  • Disparities in Care: There’s a growing gap in access to mental health services among different demographic groups.
  • Increasing Public Awareness: The stigma around mental health has decreased, with a rising demand for mental health services in healthcare.
  • Digital Innovation: Digital products and services are increasingly seen as a means to expand access to care, covering everything from screening to therapy.
  • Diverse Needs: Mental health issues are growing across all age groups, with certain demographics reaching near-crisis levels.

Funding and Investment Trends

Mental health startups in Israel raised $248 million in disclosed funding in 2023. Interestingly, over 55% of these startups remain unfunded, indicating a selective investment landscape. Managed care startups, though fewer, have garnered a significant portion of the funding, highlighting investor preference for solutions that incorporate both patient-facing care and strong back-end infrastructure.

Innovative Companies Leading the Charge

Soly Emotional Health: CEO Lior Elisha describes how the ‘Soly’ chatbot, based on EMDR and somatic experience, became a vital tool immediately following the conflict:

“From the second day of the war, the ‘Soly’ chatbot, based on EMDR and somatic experience, proved to be a very vital tool. In less than three weeks, Soly supported more than 14,500 people. The system continues to upgrade, training therapists to enhance human response, developing biofeedback monitoring tools, and providing a holistic solution for trauma treatment.”

XRHealth: Making significant strides in Israel by leading vital initiatives to support mental health and post-trauma, this advanced virtual therapeutic clinic uses virtual and augmented reality technology approved by the FDA. Along with licensed clinicians and advanced data analysis, the company provides a comprehensive therapeutic solution for patients at home or in a clinical environment.

From the first week of the war in Israel, XRHealth was actively involved in providing vital support for stress and anxiety reduction and initial treatment for PTSD in more than 30 hospitals and various rehabilitation centers across the country, becoming a key player in supporting the home front. AI-based chatbots have proven to be particularly effective.

Other Digital Mental Health Tech Platforms

In the dynamic and evolving mental health field, Israeli technology companies are not just innovating; they are redefining how we approach mental wellness.

With a range of digital therapy platforms, each offering unique solutions tailored to meet various mental health needs. Israeli companies are integrating technology with healthcare and providing innovative, accessible, and effective mental health solutions.

From AI-driven therapy programs to digital platforms facilitating therapist-patient connections, these initiatives reflect a deep understanding of the complexities of mental health and the importance of personalized care. Some companies include:

  • GGtude: This AI-based digital therapy program focuses on cognitive-behavioral therapy, leveraging user feedback for enhanced effectiveness.
  • Helping Minds: Provides a catalog of digital therapeutic content and tools, grounded in proven treatment methodologies.
  • Wellplay: Utilizes psychodrama in a digital format for emotional support, offering an innovative approach to therapy.
  • Sequel.Care: Serves as an “operating system” for integrative treatment, offering a comprehensive approach to mental health care.

Charting New Ground in Mental Health Tech

The integration of technology in mental health care in Israel is not just a response to a temporary crisis but a forward-looking approach to a longstanding issue.

As these companies continue to innovate and expand, they not only address the immediate needs arising from national crises but also lay the groundwork for a future where mental health support is more accessible, effective, and integrated into our digital lives.

Israel’s tech-driven approach to mental health demonstrates the power of technology in transforming the landscape of mental health care.

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AI in Healthcare  https://startupnationcentral.org/blog/health-tech/ai-in-healthcare/ https://startupnationcentral.org/blog/health-tech/ai-in-healthcare/#respond Wed, 27 Sep 2023 07:21:40 +0000 https://startupnationcentral.org/?p=25187 In the fast-paced world of modern medicine, the integration of Artificial Intelligence (AI) is a game-changer. Generative AI in healthcare refers to the use of advanced technologies that mimic human intelligence to streamline medical processes, enhance patient care, and drive medical innovation. The potential impact of AI in healthcare is profound, and it is valuable […]

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In the fast-paced world of modern medicine, the integration of Artificial Intelligence (AI) is a game-changer. Generative AI in healthcare refers to the use of advanced technologies that mimic human intelligence to streamline medical processes, enhance patient care, and drive medical innovation. The potential impact of AI in healthcare is profound, and it is valuable to understand its applications, benefits, and potential risks. 

Applications of AI in Healthcare 

AI is revolutionizing healthcare, enabling unprecedented advancements and enhancing medical capabilities. Some key applications include: 

  •  Wearable Health Technology: Wearable devices equipped with AI capabilities, such as smartwatches and fitness trackers, support continuous monitoring of vital signs and health parameters, promoting preventive care and early detection of health issues. 
  •  Medical Imaging: AI-powered medical imaging has significantly improved diagnostic accuracy by analyzing images from X-rays, MRIs, CT scans, and other imaging modalities. This technology helps detect diseases at an early stage, allowing for swift intervention and better patient outcomes. 
  •  Drug Discovery: AI-driven algorithms can analyze vast datasets, helping researchers find potential drug candidates more efficiently. This accelerates the drug discovery process, leading to faster development of new treatments and therapies. 
  •  Personalized Medicine: AI analyzes individual patient data, including genetics, lifestyle, and medical history, to tailor treatments that are more effective and better suited to each patient’s unique needs. 
  •  Predictive Analytics: AI-driven predictive analytics can forecast disease outbreaks and patient readmission rates, and find high-risk patients, allowing healthcare providers to distribute resources effectively and improve overall healthcare management. 
  •  Clinical Decision Support in Healthcare: AI-powered clinical decision support systems help healthcare professionals make well-informed treatment decisions based on patient data and medical knowledge, resulting in optimized care and fewer medical errors. 
  •  Robotics: Robots with AI capabilities are transforming surgical procedures by assisting surgeons in complex tasks, minimizing invasiveness, and improving patient recovery. 

Benefits of AI in Healthcare 

The integration of AI in healthcare comes with an array of advantages that revolutionize the industry: 

1. Improved Diagnosis Accuracy:

In the realm of medical diagnosis, the incorporation of AI has marked a significant leap forward. AI-enabled systems possess the extraordinary ability to discern subtle patterns and anomalies that might elude even the most skilled human clinicians. These systems have the potential to examine vast volumes of patient data, identifying nuanced trends that could otherwise be overlooked. This heightened analytical capability translates to more precise and timely diagnoses. By facilitating the early detection of diseases and conditions, AI not only enhances patient outcomes but also plays a pivotal role in preventing the progression of illnesses to more critical stages.

2. Speeding Up Treatment:

The expeditious processing power of AI technology has revolutionized the pace at which medical treatment is administered. Traditionally, diagnosis and treatment planning could be a protracted process, often involving extensive manual analysis of patient data. However, with the integration of AI, the duration of these stages has been significantly truncated. AI’s rapid data processing capabilities enable the swift assessment of medical information, empowering healthcare professionals to devise treatment plans more promptly. This acceleration is particularly crucial in cases where time-sensitive interventions can mean the difference between life and death. By facilitating quicker diagnosis and treatment initiation, AI optimizes patient care and contributes to improved medical outcomes.

3. Reduced Costs:

The economic landscape of healthcare is undergoing a transformation through the automation facilitated by AI. Administrative tasks that have traditionally demanded substantial human resources can now be streamlined through AI-driven processes. From appointment scheduling to billing and record-keeping, these automated systems are not only efficient but also cost-effective. By optimizing resource utilization and minimizing manual intervention, AI has the potential to significantly cut down operational expenses. This financial efficiency translates to more sustainable healthcare systems, making quality medical care accessible to a broader spectrum of patients.

4. Enhanced Patient Outcomes:

At the heart of AI’s impact on healthcare lies the promise of enhanced patient outcomes. The convergence of personalized medicine and AI analysis holds immense potential for improving the overall quality of care. By dissecting patient data at a granular level, AI can discern unique characteristics, needs, and responses to treatments. This intricate understanding enables healthcare professionals to tailor interventions that are precisely aligned with an individual’s requirements. The result is a higher probability of successful treatment outcomes, reduced adverse effects, and an overall improvement in patient well-being. With AI’s assistance, healthcare is evolving into a realm where treatments are not just standardized, but customized for optimal results.

Challenges and Risks of AI in Healthcare 

While the integration of AI in healthcare offers a myriad of advantages, it is important to acknowledge that this paradigm shift is not without its challenges and potential risks. These considerations are crucial to ensure that the benefits of AI are harnessed responsibly and ethically.

  • Ethical Concerns:

As AI algorithms increasingly play a role in medical decision-making, the question of ethics becomes paramount. One significant concern is the potential for bias within these algorithms. AI systems are designed to learn from large datasets, which can inadvertently include biases present in the data. If these biases are not recognized and addressed, they can lead to unequal treatment and suboptimal care for certain patient groups. Ensuring transparency in AI algorithms, including regular audits and assessments, is essential to minimize bias and maintain ethical standards. The healthcare community must also grapple with ethical questions surrounding the delegation of critical decisions to AI, ensuring that human oversight and accountability remain central to the process.

  • Data Privacy:

The vast amount of patient data generated and utilized by AI systems raises profound concerns about data privacy and security. Healthcare data is inherently sensitive, containing personal medical histories, diagnoses, and other intimate details. The collection, storage, and analysis of this data within AI systems require stringent safeguards to prevent unauthorized access, breaches, and potential misuse. Striking a delicate balance between the benefits of data-driven insights and the protection of patient privacy necessitates robust data encryption, anonymization protocols, and adherence to data protection regulations. Achieving this balance will be pivotal in maintaining patient trust and ensuring the responsible use of AI in healthcare.

  • Safety Risks:

As AI becomes involved in critical medical tasks, such as diagnosis and treatment recommendations, the safety and reliability of these AI systems are of paramount concern. Errors or misinterpretations by AI algorithms can have serious consequences for patient health. Ensuring the accuracy and reliability of AI systems requires rigorous testing, validation, and continuous monitoring. Additionally, the integration of AI must be accompanied by mechanisms that allow healthcare professionals to intervene in cases where AI recommendations may deviate from standard protocols or exhibit unexpected behavior. Establishing fail-safe measures and protocols for the seamless transition between AI-driven insights and human intervention is vital to ensuring patient safety and maintaining the trust of both healthcare providers and patients.

Future of AI in Healthcare 

While the potential benefits of AI in healthcare are vast, it is crucial to approach its adoption with a clear understanding of the associated challenges and risks. Addressing ethical concerns, prioritizing data privacy, and mitigating safety risks are central to realizing the full potential of AI in healthcare while upholding the highest standards of patient care and medical ethics.

  • Enabling more precise and personalized treatments. 
  • Empowering patients with better access to healthcare information and resources. 
  • Driving medical research and innovation at an unprecedented pace. 

The integration of AI in healthcare has the potential to revolutionize the medical landscape. By understanding its applications, benefits, and challenges, we can harness the power of AI to deliver better healthcare and improve patient well-being. 

Israeli Health Tech Ecosystem and AI in Healthcare

Israeli health tech is at the forefront of leveraging AI to address challenges and harness opportunities in the healthcare sector. With a rich ecosystem of innovative startups and established companies, Israel has become a hub for AI-driven healthcare solutions.

AI is being employed to enhance medical imaging and aid in the early detection of disease through more precise analysis of images. AI-driven drug discovery platforms are accelerating the development of new treatments, and personalized medicine approaches benefit from AI’s ability to analyze patient data on a granular level. Clinical decision support systems are becoming more sophisticated, providing healthcare professionals with valuable insights for better-informed decisions.

Here are some of the companies leading the implementation of AI-driven solutions in healthcare:

  1. K Health:
    Kang Health is a Tel Aviv-based platform established in 2016 that utilizes AI and data to offer personalized health insights. The company aims to revolutionize the way individuals understand and manage their health by providing features such as a symptom checker, personalized health insights, and a community platform for sharing experiences. They have successfully raised $30 million in funding to further their mission.
  2. MeMed Diagnostic:
    Founded in 2009 and headquartered in Tirat Carmel, Israel, MeMed Diagnostic is at the forefront of developing advanced diagnostic solutions. Their primary focus is on monitoring the immune state of patients to distinguish between bacterial and viral infections. The company has introduced innovations like the MeMed BV™ test and the MeMed Key™ platform and has fostered collaborations with global partners to expand itsreach.
  3. Diagnostic Robotics:
    Diagnostic Robotics, established in 2017 in Tel Aviv, offers an AI-driven platform dedicated to clinical decision support. Their system is designed to predict patients’ medical needs, providing a triage process that not only reduces waiting times for patients but also streamlines the care process. Their efforts have been recognized and adopted by leading healthcare providers, marking their significance in the medical field.
  4. Healthy.io:
    Based in Tel Aviv, Healthy.io specializes in transforming smartphone cameras into clinical-grade medical devices, with a focus on at-home urinalysis and digitized wound care. The company has achieved milestones such as receiving FDA clearance for its innovative home
  5. Nanox Vision:
    Nanox Vision is a pioneer in the realm of medical imaging technology and solutions. The company has developed the Nanox.ARC system, an innovative digital X-ray technology. With a series of FDA clearances for various products under its belt, Nanox Vision has showcased its advancements at major conferences and has established collaborations with global partners. Based in Neve Ilan, Israel, Nanox Vision continues to make strides in redefining medical imaging for the future.

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Global Health Challenges, Meet Israeli Health Tech Solutions https://startupnationcentral.org/blog/health-tech/global-health-challenges-meet-israeli-health-tech-solutions/ https://startupnationcentral.org/blog/health-tech/global-health-challenges-meet-israeli-health-tech-solutions/#respond Sun, 03 Sep 2023 08:04:40 +0000 https://startupnationcentral.org/?p=25124 As consumer and provider expectations zero in on healthcare that is more personal, reliable, accurate, and data-driven, the global health tech market furthering those goals is projected to grow to over $200 billion worldwide by 2024. Israel’s digital health ecosystem has become a fertile breeding ground for innovative health tech solutions. According to data from Startup […]

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As consumer and provider expectations zero in on healthcare that is more personal, reliable, accurate, and data-driven, the global health tech market furthering those goals is projected to grow to over $200 billion worldwide by 2024.

Israel’s digital health ecosystem has become a fertile breeding ground for innovative health tech solutions. According to data from Startup Nation Finder, Israel’s share of global investment increased from 1.5% in 2014 to 4.5% in 2019, and reached $1.5B in investment capital even in 2022’s financially challenging atmosphere (2021 saw $2.6B invested into Israeli HealthTech), Israeli tech is driving global health digitalization.

Contributors to a robust Israel health startup ecosystem include a well-established healthcare system with decades of digital health data, advanced AI and cybersecurity capabilities, and stakeholder support for innovative solutions.

The Trajectory of Global Healthcare: First, Close the Gap – Then, Go Full Speed Ahead

Access to basic medical care may sound obvious, but it is not obvious in many remote areas – including vast population swaths in the United States.

Through telehealth, remote monitoring, and patient engagement technologies, digital health has made tremendous inroads in equalizing access to medical care and improving health outcomes. The same health tech innovations also dramatically reduce the burnout-inducing burden on physicians and medical staff – critical components for positive long-term global health outcomes.

In parallel to equality of care, health tech promises to improve care to new levels of personalization and effectiveness. Machine learning and artificial intelligence can be harnessed to deliver more accurate diagnoses and treatment recommendations, turning databases full of anonymized medical data into a personalized suggestion for which treatment is most likely to work the best in any individual case.

The intersection of AI and the physical sciences also holds the potential for new avenues in drug development that could reduce the need for animal testing and other ethically problematic practices.

The Israel health tech sector can push world healthcare forward in these areas.

Israeli Health Tech: Drawing on Digitalization and Data

A key advantage of Israel’s health tech industry is Israel’s public healthcare system, comprised of four competing HMOs that have been digitally based for the past 25 years. This wealth of medical data – protected by Israel’s data privacy laws and cybersecurity tech expertise – is attractive to global health providers and pharmaceutical companies searching for insights and an R&D sandbox.

Many players in the Israel health startup ecosystem have positioned themselves as partners for multinational health-related corporations that want to leverage comprehensive medical data for their product or service development.

Israel’s HMOs are partially publicly funded and partially privatized. They compete for clients and revenue, prioritizing innovation in services, offerings, and work efficiency. This atmosphere of healthy competition has given rise to numerous health tech innovations designed for the Israeli medical system, but modifiable and exportable to the world.

Getting any Israeli digital health technology to where it can most help the world has its challenges.

Bringing Israeli Health Tech to Market: The Challenges

Some of the obstacles Israeli health tech startups face are common to all startups, such as early-stage access to capital. The groundbreaking idea brewing in an Israeli R&D lab will not make it to market without an investor, but an investor is unlikely to invest in a concept that hasn’t yet made it out of the lab.

Another area where startups tend to stall is in the POC stage. Despite the vast majority (approximately 80%) of POCs in the corporate funnel validating the concept, only 10-25% result in full-scale commercial implementation.

Other challenges, however, are particular to health tech, including human capital supply gaps and market education and adjustment. While Israel has excellent medical personnel – more than enough talent to support the digital health ecosystem – the technological skill gap among medical professionals is a barrier.

Adjusting Israeli technology to different international healthcare systems’ needs, expectations, and regulations is also a significant obstacle to market success.

Overcoming the Obstacles

To get promising Israeli health tech startups over the hurdles, we create connections and business engagements between health tech-relevant Israeli startups and global players looking to access high-quality healthcare innovation or fast, cost-effective R&D and clinical trial validation.

Dr. Iris Adler is a physician with hands-on experience in the ER and on humanitarian volunteer missions serving global hotspots facing socio-political crises. Dr. Adler witnessed the gaps in local and global health systems firsthand, and sees the potential for innovation to address these systemic impediments:

“In my experience, there is a pressing global lack of medical personnel. This human capital gap was exacerbated by pandemic burnout and has persisted, and in fact is worsening. In addition, many countries struggle with providing equal access to healthcare, for example in the United States. It is my firm belief that digitalization and innovation technology can significantly and meaningfully respond to these two major challenges – and that the Israeli ecosystem is equipped to deliver solutions.”

Dr. Iris Adler, Health Tech Sector Lead at Startup Nation Central.

Since the first stage in most relationships between Israeli tech startups and global organizations is a POC, optimizing POC execution has the potential to be a significant factor in raising the export success rate of Israeli health tech.

Healthcare Starts at Home

In addition to facilitating connecting Israeli health tech to the world and propelling access to global markets, Startup Nation Central works with the local medical system to improve efficiency and outcomes, while creating opportunities to upskill its personnel. While the Israeli healthcare system is a natural fit for digital health innovation, many medical professionals lack the digital literacy needed to leverage new, innovative digital health tools.

Startup Nation Central conducts roundtables and panels with Israeli medical professionals and stakeholder organizations to identify challenges, brainstorm solutions and opportunities, and encourage buy-in. The aim is to improve patient outcomes by bringing the Israeli health system fully into the digital era, as Dr. Adler explains:

“Strengthening startups and helping them enter global markets is our mission at Startup Nation Central, but we likewise want to ensure that Israeli tech and innovation are not just exported but are also incorporated into our local health system. Many of the current technologies being developed in the Israeli ecosystem will reduce friction and improve access locally for both patients and medical practitioners. For example, several Israeli startups are developing AI-powered solutions to improve diagnostic precision and speed, while reducing medical error and enhancing individualization for more effective treatment.”

Israel’s digital health startup ecosystem has the potential to transform healthcare at home and around the world. Encouraging the right connections, partnerships, and tech transfers will bring personal, effective, and accessible healthcare for all closer than ever before.

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